Protagonists: Sam, Dean, Jack, Castiel, Alternate Charlie, Donna, Alternate Bobby
Major Antagonists: Billie, The Empty
FEATURED CREATURES: Angel, Nephilim, Four Horsemen, Celestial Being, Reaper
Over Plot: Boys deal with fallout of Chuck wanting to end their story
Major Character Deaths: Adam, Jody, Lisa, Donatello, Ben, Amelia, Claire, Alternate Bobby, Eileen, Donna, Garth, Linda Tran, Ghostfacers, Cole, Alexis, Patience, Alternate Charlie, Kaia, Castiel, Billie
Minor Deaths: 2 apocalypse worlders disappear, 11 more disappear in the silo
Notes: Alternate Charlie disappears in the silo as does Alternate bobby and Donna, The Empty kills Castiel and finishes off Billie, It is implied everyone else on the planet other than Dean, Sam and Jack are gone which is another 7.7 billion.
Episode Bystander Kill Count: 7,700,000,000
Killed/Destroyed/Banished Count: 0